Dinuclear, Quadruply-stranded Compounds Comprising Palladium Or Platinum

The invention relates to a compound of formula (M2L4 where: M = a palladium or platinum metal ion; L = X = -O-, -S-, -NH-, or (-CH2-)n, where n = 1, 2 or 3; R2, R4, R5, R6 are each independently selected from -H, -F, -Cl, -Br, -I, -methyl, -ethyl, -propyl, -O-methyl, -OH, -CH2OH, and - CH2CH2OH, R7, R8, R9, R10 are each independently selected from -H, -F, -Cl, -Br, -I, - methyl, -ethyl, -propyl and -O-methyl; a pharmaceutically acceptable salt, complex thereof, compositions comprising the compound or complex. The invention further relates to the use of the compound or composition in the treatment of a cancer, a microbial infection or a virus infection, to a method of treating a cancer, a microbial infection or a viral infection comprising administering to a patient a pharmaceutically acceptable amount of the compound or composition.

Attached files:


Patents:
WO 2,009,068,885

Inventor(s): HANNON MICHAEL J [GB]

Type of Offer: Sale



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