Human Antibodies Against Hepatitis C Virus (hcv) Uses Thereof.

Isolated human monoclonal antibodies which bind to hepatitis C virus (HCV), and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced in a transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals, and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.

Patents:
MX 2,009,008,706

Inventor(s): AMBROSINO DONNA [US]; BABCOCK GREGORY J; THOMAS WILLIAM D JR; BOERING TERESA; SLOAN SUSAN

Type of Offer: Sale



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