Bicyclic Compounds Having Antimitotic And/or Antitumor Activity and Methods of Use Thereof

The present invention provides bicyclic compounds, pharmaceutically acceptable salts, prodrugs, solvates, and hydrates thereof, having antimitotic activity, anti-multidrug resistance activity, such as for example P-glycoprotein inhibition, and antitumor activity, and which inhibit paclitaxel sensitive and resistant tumor cells. Also provided are methods of utilizing these compounds for treating tumor cells and inhibiting mitosis of cancerous cells.

Patents:
WO 2,010,006,025

Inventor(s): GANGJEE ALEEM [US]

Type of Offer: Licensing



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