Use of Electrophilic Compounds for Inducing Platelet Production Or Maintaining Platelet Function

The present invention is directed to a method of inducing platelet production that includes contacting a megakaryocyte with an electrophilic compound under conditions effective to induce platelet production by the contacting megakaryocyte. Methods of treating a patient for low platelet levels, increasing the circulating half- life of platelets, and improving the quality (activity) of platelets are also disclosed herein, which involve administering the electrophilic compound to a patient an effective amount to achieve the desired effect. Pharmaceutical compositions and therapeutic systems are also disclosed for carrying out these therapeutic treatments

Patents:
WO 2,009,058,849

Inventor(s): PHIPPS RICHARD P [US]; O'BRIEN JAMIE [US]

Type of Offer: Licensing



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