Anti-cancer Vaccine Composition

Combinations of anti-cancer vaccines and inhibitory antibodies to CD223 overcome immune suppression in cancer patients. The vaccines may be isolated antigens, groups of antigens, or whole tumor cells. The inhibitory antibodies may be generated in an animal by injection of fragments of CD223. Antibodies may be monoclonal antibodies or single chain antibodies or humanized antibodies.

Patents:
US 20,100,196,394

Inventor(s): PARDOLL DREW M [US]; HUANG CHING-TAI [TW]; VIGNALI DARIO A [US]; WORKMAN CREG J [US]; POWELL JONATHAN [US]; DRAKE CHARLES C [US]

Type of Offer: Licensing



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