Steroid Analogues for Neuroprotection

Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are pharmaceutical compositions comprising the steroid analogues and methods using the novel steroid analogues for the treatment and prevention of neurodegeneration in a patient following injury to the central nervous system.

Patents:
WO 2,009,108,804

Inventor(s): MACNEVIN CHRISTOPHER [US]; STEIN DONALD G [US]; LIOTTA DENNIS C [US]; SAYEED IQBAL [US]; GUTHRIE DAVID B [US]; LOCKWOOD MARK A [

Type of Offer: Licensing



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