Derivative N-thiolated 2-oxazolidinone Antibiotics
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylococcus aureus (MRSA), and Bacillus spp., including Bacillus anthracis.
Patents:US 9,949,480 issued 2014-04-24 [
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US 10,080,725 issued 2018-09-25 [
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Inventor(s):
TUROS EDWARD [US]; MISHRA RAJESH KUMAR [US]
Type of Offer:
Licensing
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