Multilayered Protective Coating for Protecting Metallic Surfaces of Implant Materials and Use Thereof

The invention provides use of multilayered protective coating comprising of at least an inner silane layer and an outer parylene layer, for protecting metallic surfaces of implant materials from corrosion processes and release of heavy metal ions from implant into patient.

The subject of the technology offer is a polymer multi-layer coating
for protecting the surface of metal implant materials against corrosion
processes and the release of heavy metal ions from the implant into
the patient's body. The coating consists of a passive layer and multiple
polymer layers: siLane (internal) and parylene (external) plus an
additional layer of elastomer. The passive layer is between the implant
surface and the silane layer, whereas the elastomeric layer is on parylene
layer. Passive and silane layers provide good adhesion of parylene layer
to the surface while parylene layer is the actual protective layer used to
inhibit migration of metal ions from the implant surface into the body.
Elastomeric layer, due to its pLastic properties, prevents the crystalline
and rigid parylene layer from cracking. Using the offered steel coating
results in a high quality implantation material. Noteworthy, the useful
properties of the metal itself are retained after coating, while the level
of medicaL safety significantly increases, particuLarLy referring to the
affordable steel implants.
The main advantages are:
• highly effective protection against corrosion of the implant surface in
the environment of body fluids resulting in a significant reduction of
the release of metal ions into the body;
• high durability of the coating;
• simple manufacturing method;
• relatively low price.
Those features have been confirmed experimentally. Metal ion release
laboratory tests performed in the incubator, in the environment
simulating the physiological conditions inside the human body, have
shown that the application of the protective coating described above can
reduce the amount of heavy metal ions released from the steel surface
by 50+95% compared to the uncoated surface.

The offered storm activity system is the subject of patent application (EPO, USA).

The research and development efforts concerning this technology
are continued at the Faculty of Chemistry of the Jagiellonian
University. Currently the Centre for Innovations, Technology Transfer
and University Development (CITTRU) is looking for companies and
institutions interested in obtaining a license for the material and
its applications.

Attached files:
EN-P133.pdf

Patents:
WO 2,012,005,614 issued 2012-01-12   [MORE INFO]

Type of Offer: Licensing



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