A Sensitive Assay to Identify Inhibitors of HSV DNA Polymerase

Summary Investigators from Harvard Medical School have developed a novel in vitro screening assay for small molecule inhibitors of viral DNA polymerase subunits. A number of hit have been identified with this assay that show antiviral effect in the low micromolar range, and the activity profiles of the in vitro assay itself correspond well to the antiviral effect.

Applications This high throughput antiviral screening assay has utility in identification of small molecule candidates for DNA viruses. For Further Information Please Contact the Director of Business Development Katie Gordon Email: [email protected] Telephone: (617) 432-0920

Inventor(s): Coen, Donald M

Type of Offer: Licensing



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