Therapeutic Nanospheres

4-Phenylbutyrate exerts many beneficial biological effects. It appears to induce the transcription of certain promoters, as well as having a remedial effect on proteins which are aberrantly localized within the cell. In addition, it appears to cause cells to developmentally differentiate. The present invention provides nanosphere formulations of 4-phenylbutyrate and other drugs which remediate defective protein localization intracellularly. These formulations permit lower concentrations of drugs to be administered, providing both cost and safety benefits. Patent (Set) WO 98/56370; 6,207,195; 749032

Patents:
US 6,207,195

Inventor(s): Leong, Kam W

Type of Offer: Licensing



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