Biosynthetic Engineering of Cell Surface Sialic Acids

Surrounding every cell is a halo of glycoproteins, glycolipids and proteoglycans termed the glycocalyx. On these structures, the most common terminus is the sugar sialic acid which is unique in its 9-carbon structure and tissue specific derivatization. Because of its location and potential for diversity by derivatization, this sugar is often involved in cell to cell communication events, viral adhesion, and bacterial pathogenesis. Description (Set) Proposed Use (Set) Treatment of viral or bacterial infections. Pre-treatment of neural stem cells to enhance in vivo outgrowth.
Patent (Set) 6,274,568

Patents:
US 6,274,568

Inventor(s): Fralich, Thomas J.

Type of Offer: Licensing



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