Biodegradable and Biocompatible Lactide-Phosphate Copolymers, Compositions, Articles and Methods for Making the Same

The growing need for new polymer-based drug delivery materials continues to stimulate polymer research. Although several classes of synthetic polymers have been studied for controlled drug delivery and tissue engineering, polylactide (PLA) and poly (lactide-co-glycolide) (PLGA) still remain the most popular and well characterized biodegradable polymers. Due to the wide range of applications for polymer-based drug delivery, polymers often require varied physiochemical properties. Besides physical blending, one of the most plausible ways to adjust the physicochemical properties of PLA and PLGA is through copolymerizeation. Lactide copolymers with different constituent monomers can offer a broad range of physico-chemical properties and degradation rates. This invention describes several novel methods of copolymerization

Inventor(s): Leong, Kam W

Type of Offer: Licensing



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