Fusion Polypeptide Comprising S-antigen Repeat Units

The present invention relates to a fusion polypeptide comprising a) at least one fragment of the Plasmodium falciparum S-antigen or a variant thereof, wherein the fragment comprises one or a plurality of Plasmodium falciparum S-antigen repeat unit(s) or variant(s) thereof and b) at least one antigen different from the S-antigen. The present invention also relates to a pharmaceutical composition comprising that fusion polypeptide as well as to the use thereof for the treatment or prevention of an autoimmune disease, an allergic reaction, a transplantation-related complication, e.g. graft rejection or 'graft vs. host disease', and another inflammatory disease and a method for treatment or prevention of said conditions.

Patents:
US 2,009,047,009

Inventor(s): FALK KIRSTEN [DE]; ROETZSCHKE OLAF [DE]; LUCIUS RICHARD [DE]

Type of Offer: Sale



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