Schweinfurthins and Uses Thereof

Disclosed is a method for preventing or treating an undesirable condition in a subject carrying cells homozygous null for the neurofibromatosis type 1 gene or subjects that are haploinsufficient for the neurofibromatosis type 1 gene, the method comprising administering to a subject in need thereof an effective amount of a schweinfurthin or schweinfurthin analog or derivative, or a pharmaceutically acceptable salt, prodrug, hydrate, or solvate thereof. Also disclosed is a new schweinfurthin compound of the formula.

Attached files:
WO 2010127235.jpg

Patents:
WO 2,010,127,235

Inventor(s): REILLY KARLYNE [US]; TURBYVILLE THOMAS [US]; BEUTLER JOHN A [US]; WIEMER DAVID [US]

Type of Offer: Licensing



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