Stimuli-responsive Low Solubility Hydrogel Copolymers of N-isopropyl Acrylamide and Synthesis Method

Preferred embodiment stimuli-responsive low solubility copolymer hydrogel compositions of the invention include polymerized N-isopropylacrylamide and water insoluble monomer or oligomer repeating units. The repeating units are arranged within the polymer backbone of the copolymer hydrogel. In a preferred fabrication method, precursors of N-isopropylacrylamide and precursors of the water insoluble monomer of oligomer are solved in a liquid solvent to form a solution in a container. An initiator is added to the solution. Gas is bubbled through the solution, and the container is sealed. The solution is stirred while heating to a polymerization temperature and polymerization is permitted to complete to form the copolymer hydrogel composition.

Patents:
US 20,100,203,141

Inventor(s): YARIN ALEXANDER L [US]; ZHANG YIYUN [US]

Type of Offer: Licensing



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