Muteins of hNGAL and Related Proteins with Affinity for a Given Target

The present invention relates to novel muteins derived from human lipocalin 2 (hNGAL) and related proteins that bind a given non-natural ligand with detectable affinity. The invention also relates to corresponding nucleic acid molecules encoding such a mutein and to a method for their generation. The invention further relates a method for producing such a mutein. Furthermore, the invention is directed to a pharmaceutical composition comprising such a lipocalin mutein as well as to various uses of the mutein.

Patents:
WO 2,009,156,456   [MORE INFO]

Inventor(s): SKERRA ARNE [DE]; EICHINGER ANDREAS [DE]; KIM HYUN-JIN [KR]

Type of Offer: Sale



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