Methods of Making Cell Sheets, Tissue Sheets and Tissue Engineered Blood Vessels

Methods of making cell sheets, tissue sheets and tissue-engineered blood vessels are provided. The methods include culturing cells on a nanoimprinted coated scaffold under hypoxic conditions to form an aligned cell sheet and then removing the aligned cell sheet from the scaffold. The cell sheets, tissue sheets and tissue-engineered blood vessels made the methods are also disclosed. The cell sheets, tissue sheets and tissue-engineered blood vessels may be implanted in subjects to treat a variety of conditions.

Attached files:


Patents:
WO 2,010,115,187

Inventor(s): ZHAO FENG [US]; LEONG KAM W [US]

Type of Offer: Licensing



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