Problem Solver
Craig K Esser
Areas Craig K Esser is Knowledgeable in:
Analytical and Prep Chromatography
HPLC-MS, SFC-MS, UPLC-MS
HPLC-MS, SFC-MS, UPLC-MS
Techniques Craig K Esser Uses:
• Pioneered the use of Chiral SFC technology (Berger, Thar, and Jasco SFC) to rapidly analyze, resolve, and purify optically-active organic molecules using polarimetry and CD.
• Applied mass-based purification technology (Micromass FractionLynx HPLC-MS) to rapidly purify drug molecules based on UV or molecular ion detection.
• Designed, synthesized, purified, and characterized novel, optically pure, organic molecules as part of a drug discovery team using NMR, LCMS, FTIR, and TLC.
• Optimized work flow management, resource allocation, and metric analysis, resulting in cycle time reductions of 25%.
• Utilized high-throughput synthetic tools, including solid-phase resins and automated robotic liquid handlers, to synthesize large arrays of chemical libraries.
• Applied mass-based purification technology (Micromass FractionLynx HPLC-MS) to rapidly purify drug molecules based on UV or molecular ion detection.
• Designed, synthesized, purified, and characterized novel, optically pure, organic molecules as part of a drug discovery team using NMR, LCMS, FTIR, and TLC.
• Optimized work flow management, resource allocation, and metric analysis, resulting in cycle time reductions of 25%.
• Utilized high-throughput synthetic tools, including solid-phase resins and automated robotic liquid handlers, to synthesize large arrays of chemical libraries.
Craig K Esser's Problem Solving Skills:
- Prep Chromatography
- Synthetic Organic Chemistry
- SFC
Craig K Esser's Problem Solving Experience:
- • Applied the use of EthylPyridine HPLC columns for the rapid SFC-MS purification of achiral molecules and Waters HILIC for large molecules, proteins (siRNAs), and natural products.
• Pioneered the use of Chiral SFC technology (Berger, Thar, and Jasco SFC) to rapidly analyze, resolve, and purify optically-active organic molecules using polarimetry and CD.
• Applied mass-based purification technology (Micromass FractionLynx HPLC-MS) to rapidly purify drug molecules based on UV or molecular ion detection.
• Designed, synthesized, purified, and characterized novel, optically pure, organic molecules as part of a drug discovery team using NMR, LCMS, FTIR, and TLC.
• Optimized work flow management, resource allocation, and metric analysis, resulting in cycle time reductions of 25%.
• Utilized high-throughput synthetic tools, including solid-phase resins and automated robotic liquid handlers, to synthesize large arrays of chemical libraries.