Problem Solver

Gonçalo Real

Areas Gonçalo Real is Knowledgeable in:

Molecular Biology, Microbiology, Protein Production using Eucaryotic and Procaryotic systems, Vivarl vector construction (lentivirus), Cell line development

Techniques Gonçalo Real Uses:

The Animal Cell Technology Unit focuses its research on three major areas:

Biopharmaceutical process development

■Recombinant proteins including monoclonal antibodies
■Viral vaccines
■Viral vectors for gene therapy
Stem cell bioprocessing and cell therapy

Development of in-vitro models for pre-clinical research

■Brain research
■Cancer research

Gonçalo Real's Problem Solving Skills:

  1. Cell line development
  2. Viral Vector design
  3. Protein Production and Purification
  4. Microbiology
  5. Molecular Biology

Gonçalo Real's Problem Solving Experience:

  1. The Animal Cell Technology Unit (ACTU) of iBETfor which I am Project Manager is a top research group combining knowledge and competences of scientists from a wide range of disciplines (Biochemistry, Biology and Engineering). Our know-how in terms of biopharmaceuticals spans from the initial expression vector design and cell line establishment through all stages of process development and scale-up (production, purification, stability and storage). Additionally, the recognized potential of cell- and gene-based therapies led us to develop expertise in both areas. In recent years, the ACTU has been dedicating substantial effort in the development of new in vitro models for pre-clinical research.The ACTU participates in several international projects Framework European Commission Programs and is a member of CLINIGENE, an international Network of Excellence in Gene and Cell therapy and collaborates with several pharmaceutical companies, biotech SMEs and academic institutions.