Problem Solver
Ramesh Pandey
Areas Ramesh Pandey is Knowledgeable in:
• Expert in the isolation and purification of bio-active molecules from medicinal plants and microorganisms.
• Expert in the Quality Control/Quality Assurance (QC/QA) and Standardization of Traditional Medicines.
• Preparation of necessary documents for the approval by the regulatory authorities like US-FDA, WHO, NAFDAC and other agencies.
• Expert in the Quality Control/Quality Assurance (QC/QA) and Standardization of Traditional Medicines.
• Preparation of necessary documents for the approval by the regulatory authorities like US-FDA, WHO, NAFDAC and other agencies.
Techniques Ramesh Pandey Uses:
• I believe in innovation, have used innovative approaches in all my problem solving techniques.
• There is no one general method/technique to solve all problems. Each problem has to be evaluated independently and analyzed based on the availability of raw material, technical staff and the equipment. What works in advance developed countries does not work in developing and underdeveloped countries.
• There is no one general method/technique to solve all problems. Each problem has to be evaluated independently and analyzed based on the availability of raw material, technical staff and the equipment. What works in advance developed countries does not work in developing and underdeveloped countries.
Ramesh Pandey's Problem Solving Skills:
- Professional Inventor: Graft Thin-Layer Chromatography, Maggiemycin, Anhydromaggiemycin, Fredericamycin, Paclitaxel (TAXOL®) a
- Life Sciences: Development of NICOSAN for Sickle Cell Disease. Exploring the natural biodiversity through clinical trials for r
- Healthcare: Development of Traditional Herbal Medicines as Drugs for better health.
- Microbiology: Device and Method for Evaluating Microorganisms and Bio-Assay guided Screening Process.
- Research: HPLC, TLC, NMR, Mass Spectrometry (EI-MS, FAB) application in drug development.
- Chemistry: The chemistry of Medicinal Plants, Polyene Antibiotics, Peptide Antibiotics and Anthracyclines.
- Biotech: Improvement of the Daunorubicin Fermentation realized at 10,000 Liter Fermentor Scale.
- Manufacturing: Process Development for Vancomycin, Daunorubicin, Paclitaxel, NICOSAN.
- Pharmaceutical: Novel approaches for discovering pharmaceuticals and phytopharmaceuticals.s
Ramesh Pandey's Problem Solving Experience:
- • Me and my group were the first to develop the generic Vancomycin (an injectable antibiotic produced by fermentation) from isolation of the Vancomycin producing culture followed by technology development to commercial scale production under current Good Laboratory Practices (cGLP) and current Good Manufacturing Practices (cGMP) of regulatory compliance to getting the US-FDA approval.
• Me and my team brought the first drug NICOSAN for the treatment of Sickle Cell Disease from Nigeria. That received the “Orphan Drug” designation from US-FDA for US and from European Medicine Evaluation Agency (EMEA) for European Union countries after extensive Laboratory and Process Development work for the commercial scale production. We created a state-of-the-art facility in Abuja, Nigeria and the Former President of Nigeria His Excellency Mr. Olusegun Obasanjo launched the drug on July 6th, 2006 after the approval from the Nigerian Regulatory Authorities, NAFDAC for the Nigerian market.