Problem Solver
James Siverly
Areas James Siverly is Knowledgeable in:
drug formulation
semi solids formulation
controlled release
systems integration
climate change
semi solids formulation
controlled release
systems integration
climate change
Techniques James Siverly Uses:
Design of Experiments, Systematic formulation such as using a phase diagram to optimize a formulation.
James Siverly's Problem Solving Skills:
- diffusion and membrane transport
- systems integration
- OLE for process control (OPC) communications
- programming momentum modbus PLC logic using Concept software
- HPLC analysis
- oil-water-surfactant phase diagrams including liquid crystals
- drug formulation
- percutaneous absorption and transdermal drug delivery
- controlled release pharmaceutical drug development
- basic computer programming
James Siverly's Problem Solving Experience:
- I optimized critical formulation factors--drug content, polymer membrane diffusivity, and membrane thickness--to obtain a generic formulation bioequivalent to a brand name formulation.
- I produced a program to automatically calculate pertinent membrane diffusion parameters and graph the results from the raw data.
- I designed laboratory equipment to automate the sampling of diffusion through membranes.
- I developed a supervision system to monitor the integration of a PLC, GUI, and data base software.
- I developed several mathematical models to explain drug release from a dispersion of liquid crystals through skin.