Problem Solver
Sonia C
Areas Sonia C is Knowledgeable in:
Cardiac metabolic remodeling in heart failure and diabetes, Mitochondrial physiology, computational metabolic modeling, cardiac metabolism, redox metabolism (free radicals such as reactive oxygen species), enzyme kinetics.
Techniques Sonia C Uses:
Mathematical modeling
Quantitative metabolic analysis
Experimental physiology
Analysis of high throughput technologies, such as metabolomics
Microbial physiology analysis
Computational optimization of metabolic fluxes
Quantitative metabolic analysis
Experimental physiology
Analysis of high throughput technologies, such as metabolomics
Microbial physiology analysis
Computational optimization of metabolic fluxes
Sonia C's Problem Solving Skills:
- cardiac physiology
- biophysics
- mitochondrial physiology
- metabolism
- metabolic assays
Sonia C's Problem Solving Experience:
- I developed and used quantitative methods to study physiological and metabolic processes related to heart functions and diabetic cardiomyopathy from the molecular to organ level.
- I created and optimized methods to assess oxygen consumption in working muscles from rodents hearts.
- I optimized cellular and mitochondrial assays to assess respiration and enzyme activities with high-throughput equipment, multiwell plate reader and extracellular flux analyzer.
- I developed strategies and methods to determine the key controlling steps in cellular, in particular microbial, metabolism aimed at maximizing fluxes towards specific products.
- I have conceived and carried out quantitative analysis of data through techniques combining experimental with computational modeling approaches to understand cellular physiology and metabolism.
- I prepared research for publication in prestigious peer-reviewed journals and presentations at international conferences, symposia, and lectures.
- I have lectured undergraduate and graduate courses about my fields of expertise and mentored graduate students, post-doctoral fellows, and undergraduates.
- I wrote grant applications to obtain support from top funding agencies; manage project budgets and required annual report development to meet grant requirements.