Light-Therapy Reduces Transplant Risks

Light-Therapy Reduces Transplant Risks
A new light-based process could help keep organs safe for transplant.

Developed by surgeon Marcelo Cypel at the University of Toronto, the procedure relies on Cypel’s earlier work into replacing blood in a donated organ with a non-toxic liquid preservative that reduces viral and bacterial infections.

Taking the treatment to the next level, Cypel joined with professor Vanderlei Bagnato of the University of Sao Paulo to include biphotonic therapy—which combines Cypel’s profusion process with a photosensitive drug that is also introduced into the organ. Red light is then shone on the organ while ultraviolet light was shone on the circulating liquid. The combined treatment kills viruses, including HIV-1, as well as bacteria in the organ, and the liquid can be reused multiple times.

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