Sniffing Past the Blood Brain Barrier

Sniffing Past the Blood Brain Barrier
A new nasal-based drug delivery method slips medications past the blood-brain barrier with a sniff.

The blood-brain barrier membrane protects foreign substances from entering the brain—which unfortunately also means medications are kept out. The nasal-spray technology from the team at Washington University St. Louis aims to ease the process of delivering life-saving drugs to the brain using an aerosol method, which was recently tested using gold nanoparticles and locusts. In tests, the tagged nanoparaticles were seen to travel through the locusts’ blood-brain barrier in minutes, proving that the nasal delivery method does work.

Image Credit: Ben Brahim Mohammed - The blood brain barrier

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