The innovative SoloPore technology could reduce the cost of producing engineered cells to make the therapies more accessible to everyone.
Engineered cell therapy is a promising treatment for many diseases, but producing large numbers of precise cells is an expensive process. To help lower the cost, researchers from the University of Calfornia, Riverside and the City of Hope National Medical Center developed the SoloPore device. The microfluidic device uses fluid flow to move each cell into a tiny needle, creating a pore in the cell. Reversing the flow moves the cells off the needle, leaving behind a well-defined path ideal for gene delivery.