Assay for Detection of Adrenal Tumour
The invention relates to methods, assays and kits for detecting or monitoring adrenal tumours by detecting one or more adrenal steroid metabolites. The metabolites are selected from THS (tetrahydro-11-desoxycortisol), 5-PT (5-pregnenetriol), 5-PD (pregnenediol), PD (pregnanediol), PT (pregnanetriol), Et (etiolanolone), TH-DOC (tetrahydro-11- corticosterone), (5a-THA) 5a-tetra-l l-hydrocorticosterone, and 5a-THF (5a-tetra hydrocortisol. An (Androsterone) may also be measured. 6ss-OH-cortisol may be measured to monitor mitotane therapy.
ARLT WIEBKE [GB]; STEWART PAUL MICHAEL [GB]
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