Auto-synchronous Fluorescence Detection Method and Apparatus

An apparatus for time-gated fluorescence or luminescence detection includes gating means (206) arranged to alternately permit light from an excitation source (242) to be directed to a sample (235) along a first communication path (231, 232), and then permit light emitted from the sample to be directed to a detector (246) along a second communication path (237, 238) while blocking the first communication path (231, 232): The gating means (206) may comprise a single chopper wheel or apertured disc, or a rotating or oscillating arm, and may further comprise one or more reflective facets (207). The gating means (206) may be driven via a magnetic rotor, with a ferrite bead placed to offset rotor magnets with respect to drive coils, when at rest, so as to assist with self starting.

Attached files:
WO 2009137875.jpg

WO 2,009,137,875


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