A Method of Immobilising Biological Molecules to a Support and Products Thereof
A support comprising a substrate, wherein a surface of the substrate comprises functional amino or aldehyde groups, for the covalent binding of a biomolecule. The biomolecule may be a protein such as an affinity protein. The invention also provides a method for the covalent binding of a biomolecule to a surface of a support through its amino or carboxyl group. The method comprises the steps of: providing a support substrate; cleaning a surface of a support substrate; functionalising the support substrate by chemically creating hydroxyl groups on the cleaned surface of the support substrate; inducing amines on the surface of the support substrate; and covalently binding a biomolecule to the support substrate. The biomolecule may be protein such as an affinity protein.
SANDEEP KUMAR VASHIST [IE]; HARRY HOLTHOFER [IE]; KIRK LEISTER [US]
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