Targeted Induction of Aggregation of Proteins with Cross Beta Structures
The present invention belongs to the field of protein aggregation. The invention discloses a method for interfering with the function of a target protein and uses a non-naturally, user-designed molecule, designated as aggregator, that has a specificity for a target protein and which induces aggregation upon contact with said target protein. The present invention also discloses such aggregator molecules and their use in therapeutic and diagnostic applications.
SCHYMKOWITZ JOOST [BE]; ROUSSEAU FREDERIC [BE]
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