Novel mRNA splice variant of the doublecortin-like kinase gene and its use in cancer diagnosis and therapy

Methods for treating neuroblastoma in a subject are provided. The methods include administering to the subject nucleic acid that is capable of causing a significant reduction of the amount of doublecortin like protein (DCL) in the subject. The nucleic acids include antisense oligonucleotides and small interfering RNA.

Patents:
US 20,110,020,430

Inventor(s): VREUGDENHIL ERNO [NL]; VAN KUIK-ROMEIJN PETRA [NL]

Type of Offer: Sale



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