Triterpenoid Derivatives Useful As Antiproliferative Agents

Formule (I) and (II). The present invention relates to the use of a new lupane derivative of general formula (I) or (II), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, for preventing and/or inhibiting tumor growth and for treating cancer and other proliferative diseases, more particularly for treating leukemia, liver, cervical, colon and prostate cancer. The present invention also relates to the synthesis of these compounds and to pharmaceutical compositions which contain them.

Attached files:
PT 104607.jpg

Patents:
PT 104,607

Inventor(s): RIBEIRO SALVADOR JORGE ANTONIO [PT]; MENDES DOS SANTOS RITA CATARINA [PT]; CASCANTE SERRATOSA MARTA [PT]

Type of Offer: Sale



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