Method for Imaging on Thin Solid-state Interface Between Two Fluids

Described herein is a fluid cell for an optical microscopy tool having a solid state membrane having a first side and a second, opposing side; a first fluid chamber comprising a first fluid having a first refractive index located on the first side of the membrane; and, a second fluid chamber comprising a second fluid having a second refractive index located on the second side of the membrane, the second refractive index being different than the first refractive index. Also described herein is a method for imaging a single biomolecule, the method including generating a field of evanescent illumination at a solid state membrane between a first fluid and a second fluid having different refractive indexes; and detecting light emitted by optical detectors linked to the single biomolecules at the solid state membrane.

Attached files:
WO 2010111602.jpg

Patents:
WO 2,010,111,602

Inventor(s): SONI GAUTAM VIVEK [IN]; MELLER AMIT [US]

Type of Offer: Licensing



Next Patent »
« More Microscopy Patents

Share on      


CrowdSell Your Patent