Compositions and Methods for Treating Cancer with Dacarbazine Nanoemulsions
A uniform microfluidized nanoemulsion is disclosed containing an anti-cancer agent, such as dacarbazine. The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of anti-cancer agents. As a nanoemulsion, dacarbazine has a greater anti-cancer efficacy than when applied as a free solution.
NICOLOSI ROBERT [US]; TAGNE JEAN-BOSCO [US]
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