Caveolin 1-reporter Protein Knock-in Mouse

The present invention embraces a transgenic mouse whose genome harbors a nucleic acid molecule encoding caveolin-1 fused in-frame with a reporter. To control expression of the Cavl-reporter, the nucleic acid molecule further includes a selectable marker expression cassette flanked by recombinase target sites in such a manner that, upon exposure to recombinase, said selectable marker expression cassette is excised from said nucleic acid molecule.

WO 2,010,138,397

Inventor(s): STAN RADU V [US]

Type of Offer: Licensing

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