Reconstituted Tumor Microenvironment for Anticancer Drug Development
Extracellular matrix bioscaffolds capable of supporting the formation and growth of tumors from tumor cells introduced thereto containing tumor associated macrophages and carcinoma-associated fibroblast-like cells cultured under conditions effective to provide a cellular matrix capable of supporting the formation and growth of tumors from tumor cells introduced to the matrix. Bioscaffold kits and methods for using the bioscaffolds for testing, identifying and development of known or novel anticancer therapeutics are also disclosed.
BANERJEE DEBABRATA [US]; MISHRA PRAVIN J [US]; MISHRA PRASUN J [US]; GAO HUI [US]; GLOD JOHN [US]
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