System and Method for Liver Cell Culture and Maturation
The present invention relates to systems and methods for maturation, proliferation and maintenance of function in cells presenting hepatocyte characteristics and differentiated from stem cells. The cells of the present invention may be generated from stem cell grown in collagen sandwich configuration in the presence of a morphogen (e.g. S-NitrosoAcetylPenicillamine (SNAP) or Oncostatin-M (OSM) ).
Patents:WO 2,009,036,170
Inventor(s):
NOVIK ERIC [US]; YARMUSH MARTIN L [US]; SCHLOSS RENE [US]; SHARMA NRIPEN [US]
Type of Offer:
Licensing
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