Devices and Methods for Detecting and Monitoring Hiv and Other Infections and Diseases
Disclosed herein are bio-nanosensor devices and methods suitable for blood assays. The bio-nanosensors are based on thickness shear mode transducer capable of transmitting a shear wave into a biofluid adjacent to a bio-functionalized sensing interface of a piezoelectric crystal. The bio-functionalized sensing interface includes one or more antibodies and/or biomarker- specif?c ligands capable of sensing HIV. The disclosed bio-nanosensors are capable of defecting the presence of HIV virus at picogram sensitivities using no more than 10 [mu]l of blood in less than 15 minutes.
ROZMYSLOWICZ TOMASZ [US]; GAULTON GLEN N [US]; LEC RYSZARD M [US]
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