Methods to Diagnose and Immunize Against the Virus Causing Human Merkel Cell Carcinoma
The present invention provides isolated or substantially purified polypeptides, nucleic acids, and virus-like particles (VLPs) derived from a Merkel cell carcinoma virus (MCV), which is a newly-discovered virus. The invention further provides monoclonal antibody molecules that bind to MCV polypeptides. The invention further provides diagnostic, prophylactic, and therapeutic methods relating to the identification, prevention, and treatment of MCV-related diseases.
MOORE PATRICK M [US]; CHANG YUAN [US]; FENG HUICHEN [US]; BUCK CHRISTOPHER BRIAN [US]; PASTRANA DIANA V [US]
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