Therapeutic and Diagnostic Cloned Mhc-unrestricted Receptor Specific for the Muc1 Tumor Associated Antigen

The invention provides an isolated nucleic acid encoding a receptor, other than an immunoglobulin, wherein the receptor binds to a MUC1 tumor antigen independently of an major histocompatibility complex (MHC). The invention provides a method of activating a signaling pathway and/or killing a cancer cell using a receptor that is similar to or is a T cell receptor

Patents:
US 20,090,081,172

Inventor(s): FINN OLIVERA J [US]; ALAJEZ NEHAD M [CA]; SCHMIELAU JAN [DE]; ALTER MARK D [US]

Type of Offer: Licensing



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