Cytotoxic T Cell Defined Egfr Peptide and an Optimized Derivative Peptide
The invention provides a polypeptide having a sequence of amino acids consisting of IXDFGLAKL (SEQ ID NO: 1), as well as a nucleic acid encoding the polypeptide, vector comprising the nucleic acid, cell comprising the vector, and compositions thereof. The invention also provides a method of inducing a T-cell response in a patient with epithelial cancer, and a method inhibiting epithelial cancer, wherein the methods comprise administering the composition of the invention.
FERRIS ROBERT L [US]; ANDRADE PEDRO [US]; LOPEZ-ALBAITERO ANDRES [US]
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