Targeted Nanoparticles for Intracellular Cancer Therapy

This invention provides constructs comprising a targeting member immobilized on a detectable particulate, in which binding of the targeting member to a target structure on a surface of a cancer cell triggers internalization of the construct. Such constructs can be used to identify or monitor cancer cells in cell cultures or in a tissue. Such construct can also be used to kill or prevent growth of cancer cells in vivo. Also included in the invention are methods for killing or preventing growth of cancer cells in vivo.

Attached files:
US 20100284921.jpg

Patents:
US 20,100,284,921

Inventor(s): GORDON JENNIFER [US]; KNIGHT LINDA [US]

Type of Offer: Licensing



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