Co-polymer Stabilizers for Hydrofluoroalkane Dispersions
The use of biodegradable and biocompatible lactide-based nonionic amphiphiles to stabilize a model drug (salbutamol base) dispersion in hydrofluoroalkane (HFA) propellant is disclosed. The results have industrial applicability to the development of HFA-based dispersion pressurized metered-dose inhaler formulations.
DA ROCHA SANDRO R P [US]; WU LIBO [US]
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