Cells for Increased Protein Expression Comprising One Or More Release Factors and Methods of Use
The invention provides recombinant cells or recombinant restrictive cells for overexpressing one or more proteins comprising one or more release factors. The invention also provides methods for producing a recombinant protein comprising culturing the cells of the present invention under conditions such that one or more proteins are overexpressed, and then isolating the expressed recombinant protein, In certain embodiments of the present invention, the gene encoding the protein is codon optimized.
GREEN RACHEL [US]; ZAHER HANI S [US]
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