Ovarian Cancer Methylome

The present invention provides methods and kits for identifying a cell that exhibits or is predisposed to exhibiting unregulated growth by detecting hypermethylation of a gene or a regulatory region in at least one gene in the cell. Also provided are methods for diagnosis or prognosis of ovarian cancer in a subject. Also provided are methods of ameliorating ovarian cancer in a subject by administering to the subject an agent that demethylates a hypermethylated gene or regulatory region thereof.

Patents:
WO 2,010,099,489

Inventor(s): HOQUE MOHAMMAD O [US]; BRAIT MARIANA [US]; MALDONADO LEONEL [US]

Type of Offer: Licensing



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