Mlk Inhibitors and Methods of Use

Provided are compounds having an inhibitory effect on Mixed Lineage Kinases. Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by Mixed Lineage Kinase inhibition. Also provided are methods of treatment of neuropsychiatric disorders which comprise the inhibition of Mixed Lineage Kinases.

Patents:
WO 2,010,068,483

Inventor(s): GELBARD HARRIS A [US]; DEWHURST STEPHEN [US]; GOODFELLOW VAL S [US]; WIEMANN TORSTEN [US]

Type of Offer: Licensing



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