Universal Methylation Profiling Methods

This invention provides methods of derivatizing a double-stranded DNA comprising contacting double-stranded DNA with a CpG methyltransf erase and an s-adenosylmethionine analog. This invention also provides methods of sequencing DNA to determine methylation patterns. This invention also provides neobases and methods of sequencing for methylation patterns using neobases.

Patents:
WO 2,010,011,312

Inventor(s): BESTOR TIMOTHY H [US]; EDWARDS JOHN R [US]; JU JINGYUE [US]; LI XIAOXU [US]

Type of Offer: Licensing



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