Fibroblast Derived Stem Cells
The present invention provides methods and compositions relating to the production of stem cells, derived from dedifferentiated fibroblasts, and the use of such stem cells for treatment of a variety of different disorders and conditions. The invention is based on the surprising discovery that a population of stem cells, capable of differentiating into a variety of different cell types, can be generated by culturing fibroblasts under selective culture conditions.
SCHULDT ADAM J T [US]; BRINK PETER R [US]; COHEN IRA S [US]; ROSEN MICHAEL R [US]; ROBINSON RICHARD B [US]; GAUDETTE GLENN [US]
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