Filter Blood Fluid Channel Methods, Devices and Systems
A risk of thrombogenesis is minimized in a tubular fiber membrane filter by flowing blood or other fluid through a header manifold that ensures a minimum shear rate on the wetted surfaces without flow reversal, stagnation volumes, or a shear rate that is too high. In an embodiment, fluid is conveyed into a header space and into a manifold face at a perimeter of the header space. The header space has a progressively decreasing clearance that is minimal to provide for substantial shear rate and decreasing toward a minimum clearance in a region that is remote from the perimeter and vented by openings to the micro tubular membrane fibers. Other features and embodiments are described.
HOWARD JOHN [US]; LEONARD EDWARD F [US]; QIN THOMAS [US]
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