E3 Ligase Inhibitors

The present invention provides, e.g., compounds having the structure of formula (I): The present invention also provides pharmaceutical compositions that include such compounds, and methods for modulating murine double minute 2 protein (Mdm2) E3 ligase activity, particularly the Mdm2-MdmX hetero-complex E3 ligase activity, using such compounds.

Attached files:
WO 2010107485.jpg

Patents:
WO 2,010,107,485

Inventor(s): STOCKWELL BRENT R [US]; HERMAN ARIEL [US]

Type of Offer: Licensing

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