Human Anti-PD-1, PD-l1, and PD-l2 Antibodies and Uses Therefor
The present invention is based, in part, on the identification of novel human anti-PD-1, PD-L1, and PD-L2 antibodies. Accordingly, the invention relates to compositions and methods for diagnosing, prognosing, and treating conditions that would benefit from modulating PD-1, PD-L1, and/or PD-L2 activity (e.g., persistent infectious diseases, autoimmune diseases, asthma, transplant rejection, inflammatory disorders and tumors) using the novel human anti-PD-1, PD-L1, and PD-L2 antibodies described herein.
CA 2,738,252 [MORE INFO
FREEMAN GORDON [US]; AHMED RAFI [US]; JONES TIMOTHY D [GB]; CARR FRANCIS J [GB]; GREGSON JAMES P [GB]
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